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VLVbio‘s product line PEVIVA specialises in ELISA assays for the quantification of the Cell Death modes apoptosis and necrosis. Our products are used for research and clinical trials in the fields of oncology and hepatology.
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The PEVIVA product line is specialised in production and development of high end in vitro biomarkers and antibodies. The PEVIVA products specialises in ELISA assays for the quantification of the cell death modes apoptosis and necrosis in keratin 18 positive epithelial cells.
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M30 Apoptosense® ELISA is our best selling product and is a unique tool for reliable and reproducible quantitative detection of apoptosis of human, epithelial keratin 18 positive cells. Optimal applications fields for this kit are Hepatology, Oncology, Toxicology and more.
The M65® ELISA measures soluble keratin 18 (K18) released from dying cells and can be used to assess overall cell death (due to apoptosis and necrosis) of epithelial cells. The M65® ELISA is primarily intended to be used together with the M30 Apoptosense® assay, which specifically measures apoptosis. The M65® ELISA assay is registered as a medical device for in vitro diagnostic use in accordance with the CE-IVD directive.
The M65 EpiDeath® ELISA represents the next generation of Keratin 18 biomarkers. It measures the same epitopes as the M65® ELISA, but with an improved measuring technique. The M65 EpiDeath® ELISA measures the concentration of soluble Keratin 18 (K18, or Cytokeratin 18, CK18) in cell culture supernatants, serum and plasma. The K18 levels reflect the amount of total epithelial cell death, regardless of the cause of death (see background information).