M5 Keratin 18 antibody(unlabeled, 200 tests) |
(Prod. No. 10600) |
Figure
The M5 Keratin 18 antibody is a versatile tool for easy and reliable detection of human epithelial cells and tissues by a broad range of applications. These include Western blot, immunocytochemistry, immunoprecipitation, flow cytometry and immunohistochemistry of formalin fixed and paraffin embedded (FFPE) tissue sections.
Image shows staining of epithelial cells within a FFPE prostate tissue section using M5 Keratin 18 from PEVIVA. Secondary detection with anti mouse IgG biotin, streptavidin POD and DAB as substrate.
The antibody M5 Keratin 18 recognizes a conventional internal epitope present on uncleaved K18 in healthy or released from necrotic cells as well as the caspase-cleaved K18 fragment released selectively from apoptotic epithelial cells or tissues.
Therefore, M5 Keratin 18 antibody is a highly sensitive tool for the specific identification and quantification of cells of simple epithelial origin within a tissue or mixed cell population or to confirm K18 expression in a particular cell line model.
