M6 CytoKERATIN antibody(unlabeled, 200 tests) |
(Prod. No. 10650) |
Figure
Detection of CK18 in frozen section from human prostate tissue showing confined staining for CK18 in epithelial cells using M6 CytoKERATIN (upper panel) and nuclear counterstain with DAPI (lower panel). Secondary detection with anti mouse IgG ALEXA 488.
The antibody M6 CytoKERATIN 18 recognizes a conventional internal epitope present on uncleaved CK18 in healthy or released from necrotic cells as well as the caspase-cleaved CK18 fragment released selectively from apoptotic epithelial cells or tissues.
Therefore, M6 CytoKERATIN 18 antibody is a highly sensitive tool for the specific identification and quantification of cells of simple epithelial origin within a tissue or mixed cell population or to confirm CK18 expression in a particular cell line model.
